Utility Assessment of Glyceraldehyde additive for the preservation of blood glucose and its interferences with other clinical chemistry parameters

Abstract

Sodium fluoride is a commonly used preservative for blood glucose, but it causes interference in the analysis of other chemistry parameters. In order to decrease the economic burden on lab parameters and overcome the problem of interfering with chemical analysis by sodium fluoride an additive that has good glucose preserving ability without affecting other chemistry parameters is used. In this regard, we aimed the cross sectional comparative study to evaluate the utility of glyceraldehyde additive for the preservation of glucose and its interferences with other clinical chemistry parameters. The blood glucose, urea, sodium, and potassium levels in blood samples were taken from 25 volunteers in three different tubes (sodium fluoride, plain, and glyceraldehyde tube). There was no significant difference between glucose, Urea, sodium, and potassium levels of glyceraldehyde tube and Sodium fluoride tube after initial measurement of 30 minutes and later 8 hours, but glucose levels were seen significantly lower in plain tube at 8 hours measurement than initial measurements. It was seen as significant that the use of a single glyceraldehyde tube should be enough and affordable to avoid extra tube costs.